SYNTHESES OF 6''-N-METHYL-KANAMYGIN AND 3'', 4''-DIDEOXY-6''-N-METHYLKANAMYCIN B ACTIVE AGAINST RESISTANT STRAINS HAVING 6''-N-ACETYLATING ENZYMES
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چکیده
منابع مشابه
6-Chloro-N 4-methyl-N 4-phenylpyrimidine-4,5-diamine
In the title compound, C(11)H(11)ClN(4), the dihedral angle between the aromatic rings is 66.47 (8)°. In the crystal, mol-ecules are linked by N-H⋯N hydrogen bonds, generating C(5) chains propagating in [010]. Slipped aromatic π-π stacking between centrosymmetrically related pairs of pyrim-idine rings also occurs [centroid-centroid separation = 3.7634 (12)Å and slippage = 1.715 Å].
متن کامل6-Chloro-N-methyl-5-nitro-N-phenylpyrimidin-4-amine
In the title compound, C(11)H(9)ClN(4)O(2), the dihedral angle between the aromatic rings is 79.67 (8)°. π-π stacking between centrosymmetrically related pairs of pyrimidine rings occurs along [100] [centroid-centroid separations = 3.4572 (8) and 3.5433 (7) Å].
متن کامل4-Chloro-N-[N-(6-methyl-2-pyridyl)carbamothioyl]benzamide
In the title compound, C(14)H(12)ClN(3)OS, the short exocyclic N-C bond lengths indicate resonance in the thiourea part of the mol-ecule. The title compound is stabilized by an intra-molecular N-H⋯N hydrogen bond, which results in the formation of a six-membered ring. In addition, it shows a synperiplanar conformation between the thio-carbonyl group and the pyridine group. Inter-molecular N-H⋯S...
متن کاملN 4,N 6-Dimethyl-5-nitro-N 4,N 6-diphenylpyrimidine-4,6-diamine
In the title compound, C(18)H(17)N(5)O(2), the pyrimidine ring makes dihedral angles of 66.09 (12), 71.39 (13) and 56.7 (3)° with two phenyl rings and the nitro group, respectively. The dihedral angle between the two phenyl rings is 44.05 (14)°.
متن کاملN 4,N 6-Dimethyl-N 4,N 6-diphenylpyrimidine-4,5,6-triamine
In the title compound, C(18)H(19)N(5), the pyrimidine ring makes dihedral angles of 56.49 (9) and 70.88 (9)° with the phenyl rings. The dihedral angle between the two phenyl rings is 72.45 (9)°. No significant inter-molecular inter-actions are observed in the crystal structure.
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1972
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.25.743